Change in Serum Iron Level in Patients with Type 2 Diabetes Mellitus
Keywords:
Type 2 Diabetes Mellitus, Serum IronAbstract
Background: Type 2 diabetes mellitus (T2DM) is a growing global public health concern of new era, with prevalence steadily increasing especially in Bangladesh. Disturbance of serum iron metabolism causes several biochemical reactions those may be related with subsequent disruption in glucose metabolism and glycemic control. Methods: This cross-sectional analytical type of study was performed from July 2023 to June 2024, in the Biochemistry department of Mymensingh Medical College and samples were collected from the Endocrinology department of Mymensingh Medical College Hospital, Mymensingh. Purposive non-random sampling technique was used to select study subjects according to inclusion and exclusion criteria. Total 132 subjects were included. Among them, 66 subjects were selected as Group-I (case) patients with type 2 diabetes mellitus, diagnosed according to ADA criteria, aged from 30 to 65 years of both male and female. Another 66 subjects were selected as Group-II (control) non diabetic apparently healthy individuals of the same age & sex matched. Informed written consents were obtained. Baseline parameters were recorded in pre-designed data collection sheets. Fasting serum glucose and serum iron were analysed, mean ± SD was used to express all values. Results: Following comprehensive analysis, it was revealed that highly significant (P < 0.001) raised of serum iron level in patient with T2DM (140.27 ± 20.45 µg/dl) case group when compared with non-diabetic apparently healthy individuals (86.61 ± 19.34 µg/dl) control group. Also showed that, highly significant positive correlations of fasting serum glucose with serum iron in patients with T2DM (r = 0.432, P < 0.001). Conclusion: This study will provide facility to the clinicians to improve their knowledge to overall management of T2DM. So, it is recommended early evaluation & monitoring of serum iron in T2DM.
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Copyright (c) 2024 Tanvir Hasan, Mohammad Rafiqul hoque, Muntakim Mahmud Saadi, Muhammad Saiful Hasan, Abul Bashar (Author)
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