Serum Creatinine and Estimated Glomerular Filtration Rate (eGFR) In Elderly Male Persons
Keywords:
Elderly Male, Serum Creatinine, Estimated Glomerular Filtration Rate (eGFR)Abstract
Prevalence of chronic kidney diseases increases with age. This study was done to observe some aspects of renal function status in elderly male in comparison to younger male. This analytical type of cross-sectional study was carried out in the Department of Physiology, Mymensingh Medical College, Mymensingh, Bangladesh from January 2019 to December 2019. A total number of 140 male subjects were included in this study. Among them seventy (70) younger males were taken as control group (Group I), and seventy (70) elderly males were taken as study group (Group II). Serum creatinine was measured by kinetic colorimetric method and estimated glomerular filtration rate (eGFR) by using Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. Data were expressed as mean (±SD) and statistical significance of difference among the group was calculated by unpaired student’s t-test. Pearson’s correlation coefficient test was done to find the correlation of eGFR with age. In this study we found that eGFR of elderly male was significantly decreased than younger male. serum creatinine was slightly higher in elderly male persons in comparison to younger male. Although the magnitude of correlation differed, eGFR was negatively correlated with age of the subjects. Based on the study carried out it can be concluded that due to the aging process geriatric populations are more prone to the development of kidney diseases than younger individuals.
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Copyright (c) 2024 Farzana Yeasmin, Rajesh Kumar Das, Tawhidul Alam Sohan, Umme Salma, Ruhul Amin (Author)
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